Mississippi State University was originally an all-male academy; however, in the 1960s it began programs such as social work and home economics to recruit women. Epsilon Eta chapter was installed on April 30, 1966. The chapter had two chapter rooms, one formal and one informal, across the hall from each other in a dorm. They also had a dorm floor where they lived, as there were no sorority houses at the time. The chapter went inactive in 1984 and a recolonization effort was launched in 1985, but a lack of growth caused it to be closed in 1988. At closing many items were presented to Eta Zeta at Southern Miss. The chapter was re-established once again on April 13, 2013.